Basic Information
ID: ALA4424282
Type: ADME
Description: Inhibition of CYP2D6 in human liver microsomes at 10 uM using bufuralol as substrate after 15 mins by LC-MS/MS analysis relative to control
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4424282
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 412.33 | 2.49 | 2.49 |
| 421.55 | 3.75 | 3.75 |
| 407.52 | 3.64 | 3.64 |
| 421.55 | 3.89 | 3.89 |
| 435.57 | 4.02 | 4.02 |