Basic Information
ID: ALA4424357
Type: Binding
Description: Inhibition of CK1alpha/CK1delta in human U2OS cells co-expressing Bmal1-dLuc assessed as modulation circadian clock by measuring drug level causing 1 hr circadian period lengthening measured every 100 mins by luminescence assay
Organism: Homo sapiens
Cell type: U2OS
Activity Charts
Bioactivity
Activity Types for Assay ALA4424357
EC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 354.46 | 3.20 | 3.20 |
| 422.46 | 4.22 | 4.22 |
| 463.51 | 3.78 | 3.78 |
| 461.54 | 4.43 | 4.43 |
| 365.36 | 4.05 | 4.05 |
| 393.42 | 3.41 | 3.41 |
| 447.51 | 4.40 | 4.40 |
| 433.48 | 3.79 | 3.79 |
| 407.44 | 5.22 | 5.22 |
| 335.33 | 4.04 | 4.04 |
| 361.37 | 4.43 | 4.43 |
| 421.47 | 4.01 | 4.01 |
| 390.41 | 4.61 | 4.61 |
| 434.47 | 4.00 | 4.00 |
| 448.49 | 4.65 | 4.65 |
| 447.51 | 4.18 | 4.18 |
| 393.41 | 4.83 | 4.83 |
| 440.47 | 5.65 | 5.65 |
| 461.49 | 3.71 | 3.71 |
| 448.49 | 4.37 | 4.37 |