Basic Information
ID: ALA4424506
Type: Binding
Description: Inhibition of IL-6 induced STAT3 activation in human HepG2 cells at 5 uM preincubated for 2 hrs followed by IL-6 addition and measured after 4 hrs by luciferase reporter gene assay relative to control
Organism: Homo sapiens
Cell type: HepG2
Activity Charts
Bioactivity
Activity Types for Assay ALA4424506
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 248.32 | 2.76 | 2.76 |
| 250.34 | 2.29 | 2.29 |
| 309.45 | 2.30 | 2.30 |
| 361.91 | 1.28 | 1.28 |
| 325.45 | 1.32 | 1.32 |
| 338.49 | 1.50 | 1.50 |
| 325.45 | 1.32 | 1.32 |
| 323.48 | 2.74 | 2.74 |
| 351.53 | 3.52 | 3.52 |
| 350.50 | 1.60 | 1.60 |
| 335.49 | 2.84 | 2.84 |
| 355.48 | 1.56 | 1.56 |
| 378.56 | 2.38 | 2.38 |
| 325.45 | 1.28 | 1.28 |
| 295.42 | 1.91 | 1.91 |
| 364.53 | 2.04 | 2.04 |
| 323.48 | 2.69 | 2.69 |
| 336.48 | 1.26 | 1.26 |
| 281.40 | 1.57 | 1.57 |
| 352.52 | 1.89 | 1.89 |
| 351.49 | 1.81 | 1.81 |
| 309.45 | 2.35 | 2.35 |
| 337.46 | 1.68 | 1.68 |
| 309.45 | 2.35 | 2.35 |