Basic Information
ID: ALA4424659
Type: Binding
Description: Activation of human GIRK1/2 expressed in HEK293 cells co-expressing rat mGlu8 by thallium flux assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4424659
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 401.42 | 3.23 | 3.23 |
| 280.29 | 1.37 | 1.37 |
| 365.32 | 2.05 | 2.05 |
| 323.36 | 1.82 | 1.82 |
| 359.39 | 2.47 | 2.47 |
| 360.38 | 1.87 | 1.87 |
| 459.48 | 4.27 | 4.27 |
| 381.51 | 3.79 | 3.79 |
| 379.47 | 3.01 | 3.01 |
| 415.48 | 1.23 | 1.23 |
| 395.47 | 3.00 | 3.00 |
| 383.43 | 3.13 | 3.13 |
| 325.38 | 2.06 | 2.06 |
| 367.41 | 1.84 | 1.84 |
| 364.45 | 3.59 | 3.59 |
| 363.47 | 4.20 | 4.20 |
| 365.44 | 2.99 | 2.99 |
| 373.50 | 5.54 | 5.54 |
| 379.47 | 3.06 | 3.06 |
| 364.45 | 3.59 | 3.59 |
| 405.51 | 3.80 | 3.80 |
| 383.43 | 3.13 | 3.13 |
| 366.43 | 2.38 | 2.38 |
| 366.43 | 2.38 | 2.38 |
| 413.91 | 3.95 | 3.95 |
| 329.41 | 2.20 | 2.20 |
| 351.41 | 2.60 | 2.60 |
| 297.36 | 1.64 | 1.64 |
| 364.45 | 4.53 | 4.53 |
| 373.50 | 5.54 | 5.54 |
| 376.45 | 3.41 | 3.41 |
| 433.44 | 4.01 | 4.01 |
| 405.51 | 3.73 | 3.73 |
| 383.43 | 3.13 | 3.13 |
| 373.42 | 2.53 | 2.53 |
| 379.47 | 3.30 | 3.30 |
| 433.44 | 4.01 | 4.01 |
| 379.47 | 3.30 | 3.30 |
| 399.89 | 3.64 | 3.64 |
| 390.45 | 2.86 | 2.86 |
| 339.40 | 2.45 | 2.45 |
| 434.33 | 4.30 | 4.30 |
| 363.47 | 4.20 | 4.20 |
| 380.52 | 5.00 | 5.00 |
| 434.33 | 4.30 | 4.30 |
| 395.47 | 3.00 | 3.00 |
| 401.42 | 3.27 | 3.27 |
| 384.42 | 2.52 | 2.52 |
| 384.42 | 2.52 | 2.52 |
| 381.51 | 4.40 | 4.40 |
| 393.50 | 3.63 | 3.63 |
| 374.49 | 4.94 | 4.94 |
| 401.45 | 0.84 | 0.84 |
| 391.48 | 3.56 | 3.56 |
| 442.39 | 6.85 | 6.85 |
| 364.45 | 4.53 | 4.53 |