Basic Information
ID: ALA4424777
Type: Binding
Description: Inhibition of human recombinant N-terminal His-tagged DHODH (31 to 395 residues) expressed in Escherichia coli using DHO as substrate measured after 20 mins by DCPI dye-based assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Dihydroorotate dehydrogenase(ALA1966)
Document: ALA4422683
Inhibition of human recombinant N-terminal His-tagged DHODH (31 to 395 residues) expressed in Escherichia coli using DHO as substrate measured after 20 mins by DCPI dye-based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4424777
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 397.36 | 5.85 | 5.85 |
| 442.73 | 7.22 | 7.22 |
| 369.46 | 5.94 | 5.94 |
| 424.33 | 6.93 | 6.93 |
| 371.41 | 5.71 | 5.71 |
| 383.45 | 5.58 | 5.58 |
| 428.75 | 7.58 | 7.58 |
| 357.43 | 6.07 | 6.07 |
| 373.88 | 6.58 | 6.58 |
| 438.31 | 6.57 | 6.57 |
| 387.87 | 6.22 | 6.22 |