Basic Information
ID: ALA4424826
Type: Binding
Description: Inhibition of AcrB in wild-type drug-resistant Escherichia coli BW2113 assessed as potentiation of levofloxacin-induced antimicrobial activity by measuring levofloxacin MIC at 8 ug/ml by checkerboard titration method (Rvb = 0.063 ug/ml)
Organism: Escherichia coli
Strain: BW2113
Activity Charts
Bioactivity
Activity Types for Assay ALA4424826
MIC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 317.34 | 3.64 | 3.64 |
| 337.76 | 4.30 | 4.30 |
| 347.37 | 3.65 | 3.65 |
| 311.38 | 4.02 | 4.02 |
| 283.33 | 3.24 | 3.24 |
| 269.30 | 2.85 | 2.85 |
| 295.34 | 3.39 | 3.39 |
| 351.79 | 4.30 | 4.30 |
| 297.35 | 3.63 | 3.63 |
| 347.37 | 3.65 | 3.65 |
| 331.37 | 4.21 | 4.21 |
| 241.25 | 2.07 | 2.07 |