Basic Information
ID: ALA4424854
Type: Functional
Description: Invivo inhibition of CSF1R in CSF1-induced DBA/1J mouse assessed as reduction in LPS-induced IL6 production at 10 mg/kg, po treated for 1 hr prior to CSF1-stimulation followed by LPS-addition and measured after 2 hrs by ELISA relative to control
Organism: Mus musculus
Strain: DBA/1J
Activity Charts
Bioactivity
Activity Types for Assay ALA4424854
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.55 | 3.84 | 3.84 |
| 562.66 | 3.27 | 3.27 |
| 556.71 | 4.41 | 4.41 |
| 506.60 | 3.34 | 3.34 |
| 547.65 | 2.89 | 2.89 |
| 504.58 | 3.52 | 3.52 |
| 558.68 | 6.06 | 6.06 |
| 543.66 | 4.50 | 4.50 |
| 518.61 | 3.66 | 3.66 |
| 532.64 | 3.90 | 3.90 |
| 504.58 | 3.52 | 3.52 |
| 550.65 | 2.95 | 2.95 |
| 547.65 | 2.89 | 2.89 |
| 516.59 | 5.03 | 5.03 |
| 464.52 | 3.29 | 3.29 |
| 546.67 | 3.54 | 3.54 |
| 518.61 | 3.66 | 3.66 |
| 531.65 | 4.18 | 4.18 |
| 544.65 | 3.28 | 3.28 |
| 474.56 | 4.16 | 4.16 |
| 544.70 | 4.10 | 4.10 |