Basic Information
ID: ALA4425525
Type: Binding
Description: Inhibition of c-terminal GFP-tagged human ABCG2 expressed in MDCK2 cells preincubated for 30 mins before Hoechst 33342 addition by Hoechst 33342 accumulation assay
Format: BAO_0000219
Organism: Homo sapiens
Target: ATP-binding cassette sub-family G member 2(ALA5393)
Document: ALA4425096
Inhibition of c-terminal GFP-tagged human ABCG2 expressed in MDCK2 cells preincubated for 30 mins before Hoechst 33342 addition by Hoechst 33342 accumulation assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4425525
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 355.40 | 4.83 | 4.83 |
| 331.81 | 5.69 | 5.69 |
| 526.64 | 6.34 | 6.34 |
| 469.58 | 3.64 | 3.64 |
| 354.41 | 5.00 | 5.00 |
| 313.36 | 4.75 | 4.75 |
| 311.39 | 5.35 | 5.35 |
| 311.39 | 5.35 | 5.35 |
| 341.37 | 4.74 | 4.74 |
| 357.41 | 5.06 | 5.06 |
| 358.36 | 4.65 | 4.65 |
| 315.35 | 5.18 | 5.18 |
| 322.37 | 4.91 | 4.91 |
| 353.43 | 5.60 | 5.60 |
| 423.26 | 5.65 | 5.65 |
| 314.36 | 5.78 | 5.78 |
| 345.38 | 5.19 | 5.19 |
| 343.46 | 5.76 | 5.76 |
| 321.38 | 5.02 | 5.02 |
| 326.40 | 5.65 | 5.65 |
| 423.26 | 5.65 | 5.65 |
| 353.47 | 6.34 | 6.34 |
| 342.47 | 6.37 | 6.37 |
| 397.48 | 6.00 | 6.00 |
| 437.28 | 5.95 | 5.95 |
| 379.42 | 4.70 | 4.70 |
| 321.38 | 5.52 | 5.52 |
| 406.28 | 5.81 | 5.81 |
| 315.35 | 5.18 | 5.18 |
| 353.47 | 6.34 | 6.34 |