Basic Information
ID: ALA4425533
Type: Toxicity
Description: Therapeutic index, ratio of GI50 for intrinsic cytotoxicity against MDCK2 cells over-expressing human ABCG2 top IC50 for inhibition of c-terminal GFP-tagged human ABCG2 expressed in MDCK2 cells
Activity Charts
Bioactivity
Activity Types for Assay ALA4425533
RatioGI50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 331.81 | 5.69 | 5.69 |
| 469.58 | 3.64 | 3.64 |
| 354.41 | 5.00 | 5.00 |
| 313.36 | 4.75 | 4.75 |
| 311.39 | 5.35 | 5.35 |
| 357.41 | 5.06 | 5.06 |
| 358.36 | 4.65 | 4.65 |
| 315.35 | 5.18 | 5.18 |
| 322.37 | 4.91 | 4.91 |
| 423.26 | 5.65 | 5.65 |
| 423.26 | 5.65 | 5.65 |
| 315.35 | 5.18 | 5.18 |