Basic Information
ID: ALA4425558
Type: Binding
Description: Inhibition of human ADAMTS5 using 43-mer-VQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPSPLKG as substrate in presence of Lewis rat plasma measured after 3 hrs by AlphaScreen assay
Organism: Homo sapiens
Tissue: Plasma
Activity Charts
Bioactivity
Activity Types for Assay ALA4425558
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 390.81 | 2.01 | 2.01 |
| 387.78 | 1.28 | 1.28 |
| 421.34 | 1.65 | 1.65 |
| 381.31 | 2.17 | 2.17 |
| 435.36 | 1.96 | 1.96 |
| 435.36 | 2.13 | 2.13 |
| 401.81 | 1.59 | 1.59 |
| 401.81 | 1.77 | 1.77 |