Basic Information
ID: ALA4425571
Type: ADME
Description: Ratio of plasma concentration in Lewis rat at 10 mg/kg, po bid measured after 8 hrs to IC50 for human ADAMTS5 in presence of rat plasma
Activity Charts
Bioactivity
Activity Types for Assay ALA4425571
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 390.81 | 2.01 | 2.01 |
| 387.78 | 1.28 | 1.28 |
| 421.34 | 1.65 | 1.65 |
| 381.31 | 2.17 | 2.17 |
| 435.36 | 1.96 | 1.96 |
| 435.36 | 2.13 | 2.13 |
| 401.81 | 1.59 | 1.59 |
| 401.81 | 1.77 | 1.77 |