Basic Information
ID: ALA4425580
Type: ADME
Description: Ratio of plasma concentration in Lewis rat model of MIA at 100 mg/kg, po bid administered post 3 days MIA induction measured after 4 hrs of last dosage on day 7 to IC50 for human ADAMTS5 in presence of Lewis rat plasma
Activity Charts
Bioactivity
Activity Types for Assay ALA4425580
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 421.34 | 1.65 | 1.65 |
| 435.36 | 1.96 | 1.96 |
| 435.36 | 2.13 | 2.13 |