Basic Information
ID: ALA4426453
Type: Binding
Description: Inhibition of ERK in human A375SM cells harboring BRAF V600E mutant assessed as inhibition of RSK phosphorylation measured after 4 hrs by mesoscale electrochemiluminescent sandwich assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4426453
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 358.41 | 3.65 | 3.65 |
| 372.43 | 4.21 | 4.21 |
| 323.40 | 3.79 | 3.79 |
| 321.38 | 3.72 | 3.72 |
| 361.41 | 3.24 | 3.24 |
| 375.41 | 4.65 | 4.65 |
| 386.46 | 4.52 | 4.52 |
| 344.38 | 3.97 | 3.97 |
| 384.44 | 4.14 | 4.14 |
| 373.42 | 3.61 | 3.61 |
| 376.39 | 4.04 | 4.04 |
| 349.44 | 4.50 | 4.50 |
| 388.43 | 3.91 | 3.91 |