Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as decrease in calcein-AM transport at 10'-4 M after 30 mins by fluorescence assa...

Basic Information

ID: ALA4426526

Type: Binding

Description: Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as decrease in calcein-AM transport at 10'-4 M after 30 mins by fluorescence assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: MDCK

Target:  Multidrug resistance-associated protein 1(ALA3004)

Document:  ALA4425124

Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as decrease in calcein-AM transport at 10'-4 M after 30 mins by fluorescence assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
607.716.746.74
593.686.356.35
515.615.475.47
611.725.945.94
545.645.565.56
526.595.035.03
531.615.175.17
641.755.995.99
593.686.956.95
625.756.336.33
517.584.784.78
512.574.644.64
609.757.317.31
577.686.836.83