Basic Information
ID: ALA4426655
Type: Binding
Description: Inhibition of CFTR in human intestinal organoids assessed as reduction in forskolin-induced oganoids swelling incubated for 4 hrs with cholera toxin followed by subsequent stimulation with 0.1 uM forskolin by calcein AM staining based confocal microscopy
Format: BAO_0000019
Organism: Homo sapiens
Tissue: Intestine
Subcellular Fraction: Organoids
Target: Cystic fibrosis transmembrane conductance regulator(ALA4051)
Document: ALA4425128
Inhibition of CFTR in human intestinal organoids assessed as reduction in forskolin-induced oganoids swelling incubated for 4 hrs with cholera toxin followed by subsequent stimulation with 0.1 uM forskolin by calcein AM staining based confocal microscopy: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4426655
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 180.16 | -3.22 | -3.22 |
| 2498.25 | ||
| 1297.23 |