Drug level in rat hepatocytes treated with 25-Chloro-18-methyl-13,14,17,20,22,23-hexahydro-1H,7H-15,19-methano-8,12-(metheno)-4,6,2,14,15,22-benzodiox...

Basic Information

ID: ALA4426704

Type: ADME

Description: Drug level in rat hepatocytes treated with 25-Chloro-18-methyl-13,14,17,20,22,23-hexahydro-1H,7H-15,19-methano-8,12-(metheno)-4,6,2,14,15,22-benzodioxatetraazacyclopentacosine-3,7,21,28(1H,16H)-tetrone assessed as esterase-mediated compound formation at 4 uM after 40 mins by ultraperformance liquid chromatographic method

Format: BAO_0000219

Organism: Rattus norvegicus

Target:  Unchecked(ALA612545)

Document:  ALA4425130

Drug level in rat hepatocytes treated with 25-Chloro-18-methyl-13,14,17,20,22,23-hexahydro-1H,7H-15,19-methano-8,12-(metheno)-4,6,2,14,15,22-benzodioxatetraazacyclopentacosine-3,7,21,28(1H,16H)-tetrone assessed as esterase-mediated compound formation at 4 uM after 40 mins by ultraperformance liquid chromatographic method: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
30.03-0.18-0.18
470.962.762.76