Basic Information
ID: ALA4426977
Type: Binding
Description: Inhibition of HIV1 RT K103N mutant using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincubated for 10 mins followed substarte addition measured after 30 mins by FRET assay
Format: BAO_0000357
Organism: Human immunodeficiency virus 1
Target: Human immunodeficiency virus type 1 reverse transcriptase(ALA247)
Document: ALA4425139
Inhibition of HIV1 RT K103N mutant using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincubated for 10 mins followed substarte addition measured after 30 mins by FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4426977
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 410.43 | 5.04 | 5.04 |
| 405.50 | 5.78 | 5.78 |
| 463.43 | 6.74 | 6.74 |
| 441.48 | 6.06 | 6.06 |