Basic Information
ID: ALA4427029
Type: Binding
Description: Selectivity index, ratio of IC50 for wild type EGFR kinase domain (unknown origin) to IC50 for EGFR kinase domain L858R/T790M mutant (unknown origin)
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4427029
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 542.60 | 2.11 | 2.11 |
| 570.65 | 3.15 | 3.15 |
| 572.67 | 3.40 | 3.40 |
| 528.57 | 2.10 | 2.10 |
| 556.63 | 2.59 | 2.59 |
| 570.65 | 2.98 | 2.98 |
| 559.63 | 3.34 | 3.34 |
| 554.66 | 3.45 | 3.45 |
| 653.79 | 3.62 | 3.62 |
| 570.65 | 3.15 | 3.15 |
| 555.56 | 4.78 | 4.78 |