Assay Report Card

Basic Information

ID: ALA4427057

Type: Functional

Description: Inhibition of EGFR kinase domain L858R/T790M mutant phosphorylation in human NCI-H1975 cells xenografted BALB/c mouse at 50 mg/kg, po qd for 14 consecutive days by Western blot method

Organism: Mus musculus

Strain: BALB/c

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
570.653.153.15