Basic Information
ID: ALA4427198
Type: ADME
Description: Intrinsic clearance in human liver microsomes at 1 to 2.5 uM in presence of NADPH
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA4427198
CL
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 400.22 | 3.17 | 3.17 |
| 565.58 | 6.29 | 6.29 |
| 425.56 | 2.58 | 2.58 |
| 485.03 | 3.60 | 3.60 |
| 353.40 | 1.21 | 1.21 |
| 371.46 | 2.36 | 2.36 |
| 463.51 | 3.26 | 3.26 |
| 503.65 | 3.35 | 3.35 |
| 455.54 | 2.13 | 2.13 |
| 483.02 | 2.53 | 2.53 |
| 455.58 | 3.65 | 3.65 |
| 428.51 | 1.56 | 1.56 |
| 477.61 | 2.81 | 2.81 |
| 441.55 | 3.26 | 3.26 |
| 434.55 | 0.84 | 0.84 |
| 427.53 | 3.01 | 3.01 |
| 429.50 | 1.59 | 1.59 |
| 502.54 | 2.76 | 2.76 |
| 433.56 | 1.45 | 1.45 |
| 478.60 | 1.88 | 1.88 |
| 492.62 | 2.19 | 2.19 |
| 478.60 | 1.88 | 1.88 |
| 450.54 | 1.28 | 1.28 |
| 455.58 | 3.65 | 3.65 |
| 449.55 | 2.04 | 2.04 |
| 436.52 | -0.12 | -0.12 |
| 450.54 | 1.28 | 1.28 |
| 505.42 | 3.31 | 3.31 |
| 494.60 | 0.98 | 0.98 |
| 469.61 | 4.04 | 4.04 |
| 456.57 | 2.34 | 2.34 |
| 439.54 | 3.01 | 3.01 |
| 441.55 | 2.91 | 2.91 |
| 453.56 | 3.40 | 3.40 |
| 463.59 | 1.46 | 1.46 |
| 449.60 | 1.82 | 1.82 |
| 492.62 | 2.44 | 2.44 |
| 487.43 | 3.17 | 3.17 |
| 518.66 | 2.81 | 2.81 |
| 457.55 | 2.37 | 2.37 |
| 384.46 | 2.78 | 2.78 |
| 413.50 | 2.62 | 2.62 |
| 457.62 | 3.58 | 3.58 |
| 420.51 | 2.19 | 2.19 |
| 428.51 | 2.95 | 2.95 |
| 492.58 | 1.52 | 1.52 |
| 456.57 | 2.16 | 2.16 |
| 467.47 | 3.16 | 3.16 |
| 499.59 | 3.60 | 3.60 |
| 492.62 | 2.44 | 2.44 |