Basic Information
ID: ALA4427221
Type: Binding
Description: Antagonist activity at human recombinant P2X7 receptor expressed in 1321N1 cells assessed as inhibition of BzATP-induced calcium mobilization incubated for 30 mins measured after 180 seconds by calcium-4 dye based FLIPR assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4427221
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 431.85 | 5.32 | 5.32 |
| 421.81 | 4.05 | 4.05 |
| 435.84 | 4.43 | 4.43 |
| 385.83 | 3.55 | 3.55 |
| 474.79 | 5.21 | 5.21 |
| 420.82 | 4.50 | 4.50 |
| 462.90 | 5.54 | 5.54 |
| 406.80 | 4.20 | 4.20 |
| 434.85 | 4.76 | 4.76 |
| 446.86 | 5.07 | 5.07 |
| 462.90 | 5.49 | 5.49 |