Basic Information
ID: ALA4427238
Type: Binding
Description: Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced pore formation incubated for 20 mins followed by stimulation with BzATP for 30 mins by YO-PRO dye based fluorescence plate reader method
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: P2X purinoceptor 7(ALA4805)
Document: ALA4425156
Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced pore formation incubated for 20 mins followed by stimulation with BzATP for 30 mins by YO-PRO dye based fluorescence plate reader method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4427238
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 390.91 | 3.77 | 3.77 |
| 452.93 | 4.33 | 4.33 |