Basic Information
ID: ALA4427245
Type: Functional
Description: Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilization incubated for 20 mins before L-glutamate addition
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4427245
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 374.78 | 3.53 | 3.53 |
| 318.38 | 2.91 | 2.91 |
| 304.35 | 2.60 | 2.60 |
| 340.33 | 2.88 | 2.88 |
| 373.24 | 3.91 | 3.91 |
| 303.37 | 3.21 | 3.21 |
| 318.38 | 2.91 | 2.91 |
| 338.80 | 3.25 | 3.25 |
| 338.80 | 3.25 | 3.25 |
| 338.80 | 3.25 | 3.25 |
| 356.79 | 3.39 | 3.39 |
| 390.34 | 3.76 | 3.76 |
| 318.38 | 2.91 | 2.91 |
| 354.36 | 3.19 | 3.19 |
| 338.80 | 3.25 | 3.25 |
| 352.37 | 2.75 | 2.75 |
| 304.35 | 2.60 | 2.60 |
| 347.35 | 2.61 | 2.61 |
| 318.38 | 2.91 | 2.91 |
| 322.34 | 2.74 | 2.74 |
| 336.37 | 3.05 | 3.05 |
| 304.35 | 2.60 | 2.60 |
| 333.44 | 3.99 | 3.99 |