Basic Information
ID: ALA4427798
Type: Binding
Description: Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP addition measured after 20 mins by ADPglo assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4427798
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 555.48 | 6.46 | 6.46 |
| 629.64 | 4.88 | 4.88 |
| 622.62 | 5.15 | 5.15 |
| 556.47 | 5.93 | 5.93 |
| 605.52 | 5.30 | 5.30 |
| 639.07 | 5.66 | 5.66 |
| 573.52 | 6.62 | 6.62 |
| 605.52 | 5.30 | 5.30 |