Basic Information
ID: ALA4427803
Type: Functional
Description: In vivo inhibition of CENP-E in human Colo205 cells xenografted in nude mouse assessed as phosphorylated HH3 accumulation levels in tumor measured by band intensity at 100 mg/kg, ip administered qd after 24 hrs by Western blot analysis relative to control
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4427803
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 629.64 | 4.88 | 4.88 |
| 605.52 | 5.30 | 5.30 |