Basic Information
ID: ALA4427852
Type: Binding
Description: Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-COOH as substrate in presence of ATP by IMAP fluorescence polarization assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Interleukin-1 receptor-associated kinase 4(ALA3778)
Document: ALA4425185
Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-COOH as substrate in presence of ATP by IMAP fluorescence polarization assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4427852
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 325.33 | 0.57 | 0.57 |
| 460.54 | 1.98 | 1.98 |
| 504.64 | 3.41 | 3.41 |
| 327.37 | 1.89 | 1.89 |
| 362.39 | 2.11 | 2.11 |
| 391.44 | 2.05 | 2.05 |
| 337.34 | 0.81 | 0.81 |
| 459.55 | 3.62 | 3.62 |
| 391.44 | 2.05 | 2.05 |
| 369.39 | -0.78 | -0.78 |
| 447.54 | 3.34 | 3.34 |
| 461.53 | 2.16 | 2.16 |
| 476.59 | 2.63 | 2.63 |
| 502.62 | 3.02 | 3.02 |
| 356.77 | 1.88 | 1.88 |
| 391.44 | 2.05 | 2.05 |
| 483.54 | 2.67 | 2.67 |
| 488.60 | 2.63 | 2.63 |
| 485.55 | 2.58 | 2.58 |
| 419.37 | 2.20 | 2.20 |
| 390.45 | 2.66 | 2.66 |
| 321.34 | 1.83 | 1.83 |
| 504.60 | 1.70 | 1.70 |
| 310.32 | 0.96 | 0.96 |
| 391.44 | 2.05 | 2.05 |
| 391.44 | 2.05 | 2.05 |
| 395.42 | 1.29 | 1.29 |
| 322.33 | 1.23 | 1.23 |
| 392.42 | 1.45 | 1.45 |
| 435.49 | 2.07 | 2.07 |
| 329.36 | -0.42 | -0.42 |
| 469.51 | 2.99 | 2.99 |
| 482.55 | 3.28 | 3.28 |
| 481.56 | 3.88 | 3.88 |
| 356.77 | 1.88 | 1.88 |
| 407.43 | 1.06 | 1.06 |
| 471.53 | 2.60 | 2.60 |