Basic Information
ID: ALA4427863
Type: Binding
Description: Ratio of IC50 for IRAK4 inhibition in human THP1-XBlue cells to IC50 for inhibition of human IRAK4
Format: BAO_0000219
Organism: Homo sapiens
Target: Interleukin-1 receptor-associated kinase 4(ALA3778)
Document: ALA4425185
Ratio of IC50 for IRAK4 inhibition in human THP1-XBlue cells to IC50 for inhibition of human IRAK4: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4427863
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 325.33 | 0.57 | 0.57 |
| 460.54 | 1.98 | 1.98 |
| 362.39 | 2.11 | 2.11 |
| 337.34 | 0.81 | 0.81 |
| 369.39 | -0.78 | -0.78 |
| 419.37 | 2.20 | 2.20 |
| 390.45 | 2.66 | 2.66 |
| 504.60 | 1.70 | 1.70 |
| 391.44 | 2.05 | 2.05 |
| 356.77 | 1.88 | 1.88 |