Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS1...

Basic Information

ID: ALA4428279

Type: Binding

Description: Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS1 substrate

Format: BAO_0000357

Organism: Human immunodeficiency virus 1

Target: Human immunodeficiency virus type 1 reverse transcriptase(ALA247)

Document: ALA4428027

Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS1 substrate: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4428279

IC50

Total(66)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
325.32	2.19	2.19
295.30	2.18	2.18
381.40	3.99	3.99
329.74	2.84	2.84
328.33	1.80	1.80
339.35	2.20	2.20
334.34	2.07	2.07
334.34	2.07	2.07
334.34	2.07	2.07
310.31	2.24	2.24
340.34	2.25	2.25
303.32	1.03	1.03
339.35	2.20	2.20
369.38	2.21	2.21
323.35	2.50	2.50
311.30	0.98	0.98
335.32	2.12	2.12
340.34	2.25	2.25
377.32	3.21	3.21
325.32	2.19	2.19
309.33	2.49	2.49
335.32	2.12	2.12
355.35	2.20	2.20
329.74	2.84	2.84
340.34	2.25	2.25
311.30	1.89	1.89
339.35	2.20	2.20
340.34	2.25	2.25
311.30	1.89	1.89
309.33	2.19	2.19
378.31	3.26	3.26
339.35	2.20	2.20
325.32	1.90	1.90
326.31	1.95	1.95
328.33	1.80	1.80
339.35	2.20	2.20
334.34	2.07	2.07
355.35	2.20	2.20
355.35	2.20	2.20
335.32	2.12	2.12
369.38	2.21	2.21
340.34	2.25	2.25
369.38	2.21	2.21
340.34	2.25	2.25
313.29	2.32	2.32
344.75	2.90	2.90
344.75	2.90	2.90
340.34	2.25	2.25
369.38	2.21	2.21
326.31	1.95	1.95
378.31	3.26	3.26
340.34	2.25	2.25
311.30	1.64	1.64
309.33	2.49	2.49
311.30	1.89	1.89
335.32	2.12	2.12
310.31	2.24	2.24
326.31	1.95	1.95
369.38	2.21	2.21
310.31	2.24	2.24
369.38	2.21	2.21
309.33	2.19	2.19
323.35	2.50	2.50
378.31	3.26	3.26
339.35	2.20	2.20
340.34	2.25	2.25