Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in DNA 3'-end cleavage using HTS2 substrate

Basic Information

ID: ALA4428280

Type: Binding

Description: Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in DNA 3'-end cleavage using HTS2 substrate

Format: BAO_0000357

Organism: Human immunodeficiency virus 1

Target: Human immunodeficiency virus type 1 reverse transcriptase(ALA247)

Document: ALA4428027

Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in DNA 3'-end cleavage using HTS2 substrate: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4428280

IC50

Total(65)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
325.32	2.19	2.19
295.30	2.18	2.18
329.74	2.84	2.84
328.33	1.80	1.80
339.35	2.20	2.20
334.34	2.07	2.07
334.34	2.07	2.07
334.34	2.07	2.07
310.31	2.24	2.24
340.34	2.25	2.25
303.32	1.03	1.03
339.35	2.20	2.20
369.38	2.21	2.21
323.35	2.50	2.50
311.30	0.98	0.98
335.32	2.12	2.12
340.34	2.25	2.25
377.32	3.21	3.21
325.32	2.19	2.19
309.33	2.49	2.49
335.32	2.12	2.12
355.35	2.20	2.20
329.74	2.84	2.84
340.34	2.25	2.25
311.30	1.89	1.89
339.35	2.20	2.20
340.34	2.25	2.25
311.30	1.89	1.89
309.33	2.19	2.19
378.31	3.26	3.26
339.35	2.20	2.20
325.32	1.90	1.90
326.31	1.95	1.95
328.33	1.80	1.80
339.35	2.20	2.20
334.34	2.07	2.07
355.35	2.20	2.20
355.35	2.20	2.20
335.32	2.12	2.12
369.38	2.21	2.21
340.34	2.25	2.25
369.38	2.21	2.21
340.34	2.25	2.25
313.29	2.32	2.32
344.75	2.90	2.90
344.75	2.90	2.90
340.34	2.25	2.25
369.38	2.21	2.21
326.31	1.95	1.95
378.31	3.26	3.26
340.34	2.25	2.25
311.30	1.64	1.64
309.33	2.49	2.49
311.30	1.89	1.89
335.32	2.12	2.12
310.31	2.24	2.24
326.31	1.95	1.95
369.38	2.21	2.21
310.31	2.24	2.24
369.38	2.21	2.21
309.33	2.19	2.19
323.35	2.50	2.50
378.31	3.26	3.26
339.35	2.20	2.20
340.34	2.25	2.25