Basic Information
ID: ALA4428507
Type: Binding
Description: Inhibition of CRT CVIET haplotype mutant in Plasmodium falciparum K1 isolate MRA-159 infected in erythrocytes assessed as chloroquine-coumarin probe accumulation at 10 uM after 10 hrs by Hoechst 33342 staining based flow cytometry (Rvb = 35.57 +/- 3.84%)
Format: BAO_0000219
Organism: Plasmodium falciparum K1
Strain: isolate MRA-159
Target: Unchecked(ALA612545)
Document: ALA4428038
Inhibition of CRT CVIET haplotype mutant in Plasmodium falciparum K1 isolate MRA-159 infected in erythrocytes assessed as chloroquine-coumarin probe accumulation at 10 uM after 10 hrs by Hoechst 33342 staining based flow cytometry (Rvb = 35.57 +/- 3.84%): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4428507
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 266.39 | 3.53 | 3.53 |
| 197.28 | 2.78 | 2.78 |
| 508.45 | 5.68 | 5.68 |
| 477.05 | 5.09 | 5.09 |
| 344.91 | 4.34 | 4.34 |
| 430.98 | 5.52 | 5.52 |
| 292.43 | 3.24 | 3.24 |
| 226.30 | 3.58 | 3.58 |
| 260.75 | 4.23 | 4.23 |
| 330.88 | 3.99 | 3.99 |
| 322.45 | 3.33 | 3.33 |
| 304.44 | 4.37 | 4.37 |
| 320.44 | 3.34 | 3.34 |
| 319.45 | 3.31 | 3.31 |
| 419.57 | 4.88 | 4.88 |
| 211.69 | 1.91 | 1.91 |
| 403.55 | 4.28 | 4.28 |
| 300.20 | 4.28 | 4.28 |
| 448.99 | 4.49 | 4.49 |
| 215.30 | 1.89 | 1.89 |
| 431.00 | 5.64 | 5.64 |
| 272.39 | 4.30 | 4.30 |
| 291.39 | 3.48 | 3.48 |
| 399.51 | 4.85 | 4.85 |
| 306.45 | 3.48 | 3.48 |
| 213.28 | 2.32 | 2.32 |
| 338.45 | 2.30 | 2.30 |
| 308.47 | 3.81 | 3.81 |
| 200.28 | 1.34 | 1.34 |
| 323.48 | 2.74 | 2.74 |
| 324.47 | 2.78 | 2.78 |
| 417.53 | 3.81 | 3.81 |
| 216.33 | 1.65 | 1.65 |
| 413.30 | 5.21 | 5.21 |
| 306.45 | 3.48 | 3.48 |
| 296.44 | 3.34 | 3.34 |
| 416.30 | 3.78 | 3.78 |
| 432.35 | 4.09 | 4.09 |