Assay Report Card

Basic Information

ID: ALA4428507

Type: Binding

Description: Inhibition of CRT CVIET haplotype mutant in Plasmodium falciparum K1 isolate MRA-159 infected in erythrocytes assessed as chloroquine-coumarin probe accumulation at 10 uM after 10 hrs by Hoechst 33342 staining based flow cytometry (Rvb = 35.57 +/- 3.84%)

Organism: Plasmodium falciparum K1

Strain: isolate MRA-159

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
266.393.533.53
197.282.782.78
508.455.685.68
477.055.095.09
344.914.344.34
430.985.525.52
292.433.243.24
226.303.583.58
260.754.234.23
330.883.993.99
322.453.333.33
304.444.374.37
320.443.343.34
319.453.313.31
419.574.884.88
211.691.911.91
403.554.284.28
300.204.284.28
448.994.494.49
215.301.891.89
431.005.645.64
272.394.304.30
291.393.483.48
399.514.854.85
306.453.483.48
213.282.322.32
338.452.302.30
308.473.813.81
200.281.341.34
323.482.742.74
324.472.782.78
417.533.813.81
216.331.651.65
413.305.215.21
306.453.483.48
296.443.343.34
416.303.783.78
432.354.094.09