Basic Information
ID: ALA4428511
Type: Binding
Description: Inhibition of CRT SVMNT haplotype mutant in intermediate chloroquine-resistant Plasmodium falciparum 7G8 isolate MRA-154 t assessed as reversal of chloroquine resistance by measuring reduction in chloroquine IC50 at 500 nM relative to chloroquine alone
Format: BAO_0000019
Organism: Plasmodium falciparum 7G8
Strain: isolate MRA-154
Target: Unchecked(ALA612545)
Document: ALA4428038
Inhibition of CRT SVMNT haplotype mutant in intermediate chloroquine-resistant Plasmodium falciparum 7G8 isolate MRA-154 t assessed as reversal of chloroquine resistance by measuring reduction in chloroquine IC50 at 500 nM relative to chloroquine alone: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4428511
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 197.28 | 2.78 | 2.78 |
| 508.45 | 5.68 | 5.68 |
| 477.05 | 5.09 | 5.09 |
| 344.91 | 4.34 | 4.34 |
| 292.43 | 3.24 | 3.24 |
| 330.88 | 3.99 | 3.99 |
| 304.44 | 4.37 | 4.37 |
| 448.99 | 4.49 | 4.49 |
| 306.45 | 3.48 | 3.48 |
| 324.47 | 2.78 | 2.78 |
| 296.44 | 3.34 | 3.34 |