Basic Information
ID: ALA4428692
Type: Binding
Description: Inhibition of human adenosine kinase assessed as effect on reduced nicotinamide-adenine dinculeotide appearance at 100 nM using inosine as substrate in presence of NAD, ATP incubated for 4 hrs by IMPDH based coupled enzymatic assay based non-isotopic method
Format: BAO_0000357
Organism: Homo sapiens
Target: Adenosine kinase(ALA3589)
Document: ALA4428046
Inhibition of human adenosine kinase assessed as effect on reduced nicotinamide-adenine dinculeotide appearance at 100 nM using inosine as substrate in presence of NAD, ATP incubated for 4 hrs by IMPDH based coupled enzymatic assay based non-isotopic method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4428692
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 392.15 | -0.77 | -0.77 |
| 428.49 | 2.90 | 2.90 |
| 387.18 | -0.60 | -0.60 |
| 376.16 | -0.99 | -0.99 |
| 478.29 | 1.84 | 1.84 |
| 402.19 | -0.32 | -0.32 |
| 421.62 | 0.75 | 0.75 |
| 427.21 | 1.00 | 1.00 |
| 401.21 | -0.36 | -0.36 |
| 428.49 | 3.12 | 3.12 |
| 430.48 | 4.07 | 4.07 |
| 430.48 | 4.07 | 4.07 |
| 402.19 | -0.11 | -0.11 |
| 412.49 | 3.93 | 3.93 |