Basic Information
ID: ALA4428731
Type: Functional
Description: Inhibition of PI3Kdelta in IgM membrane only homozygous transgenic mouse assessed as reduction in AKT phosphorylation in splenocytes pre-treated orally 15 mins before endotoxin-free FITC-labeled mu-chain specific anti-IgM stimulation measured 30 mins after stimulation by flow cytometry
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4428731
ED50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 442.46 | 3.21 | 3.21 |
| 442.46 | 3.21 | 3.21 |