Basic Information
ID: ALA4428883
Type: Binding
Description: Inhibition of human Nav1.7 expressed in HEK293 cells incubated for 3 to 5 mins at -125 mV holding potential by electrophysiology assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4428883
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 470.89 | 5.23 | 5.23 |
| 410.23 | 3.54 | 3.54 |
| 492.34 | 4.42 | 4.42 |
| 400.86 | 3.27 | 3.27 |
| 417.31 | 3.78 | 3.78 |
| 380.20 | 3.63 | 3.63 |
| 382.87 | 3.13 | 3.13 |
| 451.98 | 3.72 | 3.72 |
| 428.82 | 4.26 | 4.26 |
| 481.36 | 4.33 | 4.33 |
| 442.90 | 3.42 | 3.42 |
| 450.87 | 4.15 | 4.15 |
| 501.78 | 5.20 | 5.20 |
| 400.86 | 3.27 | 3.27 |
| 449.92 | 3.80 | 3.80 |
| 407.88 | 3.00 | 3.00 |
| 486.86 | 4.31 | 4.31 |
| 418.85 | 3.40 | 3.40 |
| 418.85 | 3.40 | 3.40 |
| 412.90 | 3.13 | 3.13 |
| 450.94 | 3.54 | 3.54 |
| 462.98 | 4.56 | 4.56 |
| 401.85 | 2.66 | 2.66 |
| 517.34 | 5.48 | 5.48 |
| 396.90 | 3.43 | 3.43 |
| 417.31 | 3.78 | 3.78 |
| 396.20 | 3.75 | 3.75 |
| 466.87 | 4.02 | 4.02 |
| 468.87 | 4.17 | 4.17 |
| 424.91 | 3.28 | 3.28 |
| 344.22 | 3.35 | 3.35 |
| 428.87 | 3.17 | 3.17 |
| 498.34 | 3.95 | 3.95 |
| 453.95 | 2.83 | 2.83 |
| 535.33 | 5.56 | 5.56 |
| 444.82 | 4.39 | 4.39 |
| 410.88 | 3.03 | 3.03 |