Assay Report Card

Basic Information

ID: ALA4428892

Type: ADME

Description: Inhibition of CYP2D6 in human microsomes using dextromethorphan as substrate coincubated with substrate for 30 mins measured after 5 mins in presence of NADPH by LC-MS/MS analysis

Organism: Homo sapiens

Subcellular Fraction: Microsomes

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
449.923.803.80
486.864.314.31
418.853.403.40