Basic Information
ID: ALA4428895
Type: ADME
Description: Inhibition of CYP2D6 in human microsomes using dextromethorphan as substrate incubated with enzyme and NADPH prior to substrate addition by LC-MS/MS analysis
Organism: Homo sapiens
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4428895
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 449.92 | 3.80 | 3.80 |
| 486.86 | 4.31 | 4.31 |
| 418.85 | 3.40 | 3.40 |