Basic Information
ID: ALA4428897
Type: Binding
Description: Inhibition of human Nav1.7 expressed in HEK293 cells at 5 uM incubated for 3 to 5 mins at -125 mV holding potential by electrophysiology assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Sodium channel protein type IX alpha subunit(ALA4296)
Document: ALA4428053
Inhibition of human Nav1.7 expressed in HEK293 cells at 5 uM incubated for 3 to 5 mins at -125 mV holding potential by electrophysiology assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4428897
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 362.24 | 2.49 | 2.49 |
| 365.24 | 1.53 | 1.53 |
| 375.23 | 1.89 | 1.89 |
| 396.34 | 4.04 | 4.04 |
| 351.21 | 1.42 | 1.42 |
| 425.33 | 2.90 | 2.90 |
| 366.25 | 2.88 | 2.88 |
| 325.17 | 0.80 | 0.80 |
| 335.17 | 2.34 | 2.34 |
| 371.27 | 1.74 | 1.74 |
| 384.24 | 3.00 | 3.00 |
| 395.27 | 3.90 | 3.90 |
| 437.33 | 2.41 | 2.41 |
| 365.24 | 1.42 | 1.42 |
| 296.17 | 2.00 | 2.00 |
| 328.24 | 2.30 | 2.30 |
| 363.18 | 1.91 | 1.91 |
| 334.18 | 2.07 | 2.07 |
| 282.15 | 1.61 | 1.61 |