Assay Report Card

Basic Information

ID: ALA4428934

Type: Functional

Description: In vivo inhibition of Nav1.7 in C57BL/6 mouse assessed as unbound plasma concentration required to reduce histamine-induced scratching bouts at 100 mg/kg, po administered 4 hrs prior to histamine challenge measured for 15 mins

Organism: Mus musculus

Strain: C57BL/6

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
486.864.314.31