Basic Information
ID: ALA4428988
Type: Binding
Description: Inhibition of human recombinant AKR1C3 using S-tetralol as substrate assessed as reduction in NADP+-dependent S-tetralol oxidation preincubated for 10 mins followed by protein addition by fluorometric assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Aldo-keto-reductase family 1 member C3(ALA4681)
Document: ALA4428055
Inhibition of human recombinant AKR1C3 using S-tetralol as substrate assessed as reduction in NADP+-dependent S-tetralol oxidation preincubated for 10 mins followed by protein addition by fluorometric assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4428988
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 230.26 | 3.04 | 3.04 |
| 216.24 | 2.48 | 2.48 |
| 246.33 | 3.75 | 3.75 |
| 230.26 | 3.04 | 3.04 |
| 244.29 | 3.43 | 3.43 |
| 244.29 | 3.43 | 3.43 |
| 246.33 | 3.75 | 3.75 |
| 228.29 | 3.59 | 3.59 |
| 321.40 | 2.42 | 2.42 |
| 244.29 | 3.43 | 3.43 |
| 278.33 | 2.43 | 2.43 |
| 244.29 | 3.43 | 3.43 |
| 262.33 | 2.77 | 2.77 |
| 246.33 | 3.75 | 3.75 |