Basic Information
ID: ALA4429476
Type: Binding
Description: Inhibition of recombinant human N-terminal GST-tagged FLT3 (564 to end residues) expressed by baculovirus in Sf21 insect cells measured after 10 mins in presence of [gamma-33P]ATP by scintillation counter method
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf21
Target: Tyrosine-protein kinase receptor FLT3(ALA1974)
Document: ALA4428067
Inhibition of recombinant human N-terminal GST-tagged FLT3 (564 to end residues) expressed by baculovirus in Sf21 insect cells measured after 10 mins in presence of [gamma-33P]ATP by scintillation counter method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4429476
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 448.79 | 5.46 | 5.46 |
| 403.43 | 4.40 | 4.40 |
| 409.48 | 4.54 | 4.54 |
| 393.41 | 4.07 | 4.07 |
| 478.53 | 5.54 | 5.54 |
| 418.34 | 3.54 | 3.54 |
| 429.47 | 4.91 | 4.91 |
| 427.85 | 4.73 | 4.73 |
| 504.50 | 5.55 | 5.55 |
| 407.43 | 4.38 | 4.38 |
| 486.51 | 5.41 | 5.41 |
| 405.30 | 3.80 | 3.80 |
| 436.43 | 3.81 | 3.81 |
| 406.45 | 3.82 | 3.82 |
| 478.56 | 4.50 | 4.50 |
| 424.44 | 3.96 | 3.96 |
| 407.43 | 4.38 | 4.38 |
| 436.33 | 3.68 | 3.68 |
| 411.40 | 4.21 | 4.21 |
| 411.40 | 4.21 | 4.21 |
| 393.41 | 4.07 | 4.07 |
| 468.52 | 5.27 | 5.27 |
| 407.43 | 4.09 | 4.09 |
| 506.57 | 3.88 | 3.88 |
| 435.49 | 5.13 | 5.13 |
| 392.42 | 3.65 | 3.65 |
| 460.54 | 5.40 | 5.40 |