Basic Information
ID: ALA4429527
Type: Binding
Description: Inhibition of human JAK1 assessed as reduction in phosphorylation of Biotin-Lyn-Substrate-2 after 1 hr in presence of ATP by ELISA
Format: BAO_0000357
Organism: Homo sapiens
Target: Tyrosine-protein kinase JAK1(ALA2835)
Document: ALA4428070
Inhibition of human JAK1 assessed as reduction in phosphorylation of Biotin-Lyn-Substrate-2 after 1 hr in presence of ATP by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4429527
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 361.41 | 2.01 | 2.01 |
| 379.40 | 1.96 | 1.96 |
| 415.46 | 2.06 | 2.06 |
| 414.47 | 2.67 | 2.67 |
| 415.46 | 2.06 | 2.06 |
| 428.50 | 2.98 | 2.98 |
| 447.48 | 2.32 | 2.32 |
| 429.49 | 2.37 | 2.37 |
| 429.49 | 2.37 | 2.37 |
| 413.49 | 3.27 | 3.27 |
| 468.52 | 3.72 | 3.72 |
| 468.52 | 3.72 | 3.72 |
| 429.49 | 2.37 | 2.37 |