Basic Information
ID: ALA4429658
Type: Functional
Description: Antagonist activity at human OX1 receptor expressed in CHO cell membranes assessed as inhibition of orexin A-induced Ca2+ elevation after 30 mins in presence of orexin A by FLIPR calcium 4 assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Orexin receptor 1(ALA5113)
Document: ALA4428072
Antagonist activity at human OX1 receptor expressed in CHO cell membranes assessed as inhibition of orexin A-induced Ca2+ elevation after 30 mins in presence of orexin A by FLIPR calcium 4 assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4429658
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 422.45 | 2.04 | 2.04 |
| 665.79 | 5.07 | 5.07 |
| 411.46 | 4.15 | 4.15 |
| 484.57 | 3.79 | 3.79 |
| 415.32 | 4.99 | 4.99 |
| 402.46 | 5.57 | 5.57 |
| 454.53 | 4.15 | 4.15 |