Antagonist activity at human OX1 receptor expressed in CHO cells assessed as inhibition of orexin A-induced Ca2+ elevation at 5 uM after 30 mins by FL...

Basic Information

ID: ALA4429667

Type: Functional

Description: Antagonist activity at human OX1 receptor expressed in CHO cells assessed as inhibition of orexin A-induced Ca2+ elevation at 5 uM after 30 mins by FLIPR calcium 4 assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: CHO

Target:  Orexin receptor 1(ALA5113)

Document:  ALA4428072

Antagonist activity at human OX1 receptor expressed in CHO cells assessed as inhibition of orexin A-induced Ca2+ elevation at 5 uM after 30 mins by FLIPR calcium 4 assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
422.452.042.04
665.795.075.07
411.464.154.15
484.573.793.79
415.324.994.99
402.465.575.57
454.534.154.15