Basic Information
ID: ALA4429684
Type: ADME
Description: Prodrug activation assessed as porcine liver carboxylesterase/recombinant Escherichia coli beta-galactosidase-mediated Nomega-hydroxy-L-arginine formation by measuring NO release at 500 uM preincubated for 150 mins followed by recombinant mouse iNOS and NADPH addition incubated for 30 mins followed by LDH and sodium pyruvate addition measured after 15 mins by Griess assay
Activity Charts
Bioactivity
Activity Types for Assay ALA4429684
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 374.33 | -4.19 | -4.19 |
| 453.32 | -3.71 | -3.71 |