ID: ALA4429690
Type: ADME
Description: Prodrug activation in LPS-stimulated mouse J744A.1 cells assessed as iNOS-mediated Nomega-hydroxy-L-arginine formation by measuring increase in NO release at 1 mM incubated for 2.5 hrs by Hoechst 33342/DAF-FM-DA staining based fluorescence microscopic analysis
Organism: Mus musculus
Bioactivity
Activity Types for Assay ALA4429690
Drug metabolism
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
621.47 | -1.42 | -1.42 |
374.33 | -4.19 | -4.19 |
374.33 | -4.19 | -4.19 |
453.32 | -3.71 | -3.71 |
593.41 | -1.90 | -1.90 |
593.41 | -1.90 | -1.90 |
453.32 | -3.71 | -3.71 |