Assay Report Card

Basic Information

ID: ALA4429690

Type: ADME

Description: Prodrug activation in LPS-stimulated mouse J744A.1 cells assessed as iNOS-mediated Nomega-hydroxy-L-arginine formation by measuring increase in NO release at 1 mM incubated for 2.5 hrs by Hoechst 33342/DAF-FM-DA staining based fluorescence microscopic analysis

Organism: Mus musculus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
621.47-1.42-1.42
374.33-4.19-4.19
374.33-4.19-4.19
453.32-3.71-3.71
593.41-1.90-1.90
593.41-1.90-1.90
453.32-3.71-3.71