ID: ALA4429691
Type: ADME
Description: Prodrug activation in LPS-stimulated mouse J744A.1 cells assessed as iNOS-mediated Nomega-hydroxy-L-arginine formation by measuring increase in NO release at 1 mM incubated for 2.5 hrs by Hoechst 33342/DAF-FM-DA staining based fluorescence microscopic analysis relative to Nomega-hydroxy-L-arginine
Organism: Mus musculus
Bioactivity
Activity Types for Assay ALA4429691
Drug metabolism
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
621.47 | -1.42 | -1.42 |