Basic Information
ID: ALA4429877
Type: Binding
Description: Inhibition of human glycine transporter-2 expressed in HEK293 cells assessed as reduction in [14C]glycine uptake preincubated for 10 mins followed by [14C]glycine addition measured after 3 hrs by scintillation proximity assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4429877
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 586.92 | 3.41 | 3.41 |
| 601.99 | 4.37 | 4.37 |
| 635.49 | 3.56 | 3.56 |
| 554.01 | 2.38 | 2.38 |
| 584.44 | 3.88 | 3.88 |
| 528.04 | 2.79 | 2.79 |
| 534.88 | 3.64 | 3.64 |
| 571.45 | 2.29 | 2.29 |
| 568.44 | 4.00 | 4.00 |
| 550.94 | 3.17 | 3.17 |
| 524.94 | 3.93 | 3.93 |
| 655.01 | 3.54 | 3.54 |
| 586.92 | 3.41 | 3.41 |
| 587.91 | 2.81 | 2.81 |
| 501.97 | 2.61 | 2.61 |
| 637.46 | 3.05 | 3.05 |
| 620.47 | 3.78 | 3.78 |
| 518.43 | 3.12 | 3.12 |
| 524.94 | 3.78 | 3.78 |
| 507.53 | 2.96 | 2.96 |
| 534.88 | 3.64 | 3.64 |
| 555.00 | 1.78 | 1.78 |
| 512.93 | 3.78 | 3.78 |
| 636.47 | 3.66 | 3.66 |
| 570.47 | 2.90 | 2.90 |
| 541.55 | 3.50 | 3.50 |
| 551.93 | 2.56 | 2.56 |
| 493.50 | 2.71 | 2.71 |
| 479.47 | 2.32 | 2.32 |
| 465.45 | 1.93 | 1.93 |
| 587.91 | 2.81 | 2.81 |
| 527.52 | 3.36 | 3.36 |
| 550.94 | 3.17 | 3.17 |
| 621.46 | 3.17 | 3.17 |