Assay Report Card

Basic Information

ID: ALA4429988

Type: Functional

Description: Invivo inhibition of glycine transporter-1 in Sprague-Dawley rat assessed as increase in medial prefrontal cortex glycine level at 3 to 10 mg/kg, po administered through oral gavage measured after 80 to 300 mins by LC-MS/MS analysis relative to control

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
635.493.563.56