Basic Information
ID: ALA4430043
Type: Binding
Description: Inhibition of human PI3Kalpha expressed in rat-1 fibroblasts assessed as reduction in Akt phosphorylation at Ser 473 after 1 hr by alphascreen assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4430043
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 496.57 | 4.29 | 4.29 |
| 467.53 | 3.67 | 3.67 |
| 492.54 | 3.54 | 3.54 |
| 459.55 | 4.90 | 4.90 |
| 507.52 | 4.77 | 4.77 |
| 446.56 | 2.69 | 2.69 |
| 440.51 | 3.15 | 3.15 |
| 464.53 | 3.63 | 3.63 |
| 487.56 | 4.82 | 4.82 |
| 535.53 | 4.69 | 4.69 |
| 439.52 | 3.76 | 3.76 |
| 468.56 | 4.37 | 4.37 |