Assay Report Card

Basic Information

ID: ALA4430157

Type: Binding

Description: Inhibition of AKR1C3 in human HL60 cells assessed as potentiation of etoposide-induced cytotoxicity by measuring reduction in cell viability pre-treated with 0.1 to 1 uM compound for 24 hrs followed by 1 uM etoposide exposure for additional 72 hrs by MTS assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
364.444.834.83
363.464.864.86
364.444.834.83
363.464.864.86